These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. 

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These statements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease. These results are not typical. Individual results may vary.

 

NAD+ Treatment Center was created  by a group of business investors and Certified Doctors  who have experienced the pain of chronic disease first hand  up to bring a facility to help bring this treatment to others in similar situations. NAD+ Treatment Center  combines the latest treatments through NAD+ Therapy, the best practices of counseling, and the best natural approach to treatment to produce lasting recovery. NAD+ Treatment Center treats patients seeking recovery from drug addiction and those seeking to feel revitalized and with more energy with our renowned Anti Aging Therapy.  NAD+ Treatment Center is the best NAD+ therapy program for brain restoration for those battling with Drug Addiction. The program is  designed to restore and provide lasting recovery for people struggling with; Alcohol Dependence, Heroin Detox, Opioid Dependence, Stress and Anxiety, Benzodiazepine Detox, Substance Abuse, Methadone, Suboxone Detox, Ketamine Detox, just to name a few. The center is located in San Diego, California in the Heart of Hillcrest we have served families from all over the US. Most patients come from California, Texas, Connecticut, Nevada, Kansas, Louisiana and New York.

 


The Biology Connect, Inc. 2019
NAD+ Treatment Center San Diego , 4080 Centre Street #207, San Diego, CA, 92103.

ANTI-AGING 

There are numerous therapeutic benefits from intravenous nicotinamide adenine dinucleotide (NAD+) therapy for anti-aging. NAD+ has been observed to decline with age and thus hinders the natural repair mechanisms within the cell. One important benefit from replenishing cells with NAD+ is the activation of restorative enzymes involved with regulating that inflammation.

Pat, Previous Patient

Why Does NAD+ Decline with Age?

 

Declining NAD+ associated with aging is due to the inability of the cell to recycle NAD+, or to synthesize new NAD+. Enzymes either break down NAD+ into its derivatives or reduce the NAD+ in the form NADH. Two enzymes notorious for the degradation of NAD+ include PARP and CD38.

NAD declines with age
NAD+ Declines with Age

Massudi, H., Grant, R., Braidy, N., Guest, J., Farnsworth, B., & Guillemin, G. J. (2012). Age-Associated Changes In Oxidative Stress and NAD Metabolism In Human Tissue. PLoS ONE, 7(7). doi:10.1371/journal.pone.0042357

"The NAD enhanced all of my activities... Everything I do, I do with a little more joy. Life has been more fun... Everything seems to be 40 years old again."
- Previous patient, Pat 

Reverse Age by Replenishing NAD+

A recent scientific discovery reveals a promising solution to this critical issue with aging. Scientists at Harvard Medical School have found a way to reverse the accumulation of DNA damage. An article in the latest issue of Science explains how NAD+ regulates protein-protein interactions involved in DNA repair.

 

“We recently showed that raising NAD levels in mice can reverse aspects of aging within just one week of treatment.” said David Sinclair, Ph.D., professor of genetics at Harvard University.

PARP Enzymes Require NAD+ to Repair DNA

 

There are 17 poly (ADP-ribose) polymerases (PARPs) enzymes that participate in repairing damaged DNA. Most DNA damage occurs from oxidative stress, or inflammation. PARP enzymes bind to the broken DNA strand and acts as a signal to recruit other repair enzymes. In order for PARP enzymes to repair DNA effectively is NAD+ a necessary ingredient.

PARP enzymes are crucial to cellular health, but over expression of excessive DNA damage has its consequences. Available NAD+ is significantly depleted within the cell from excessive PARP expression. Without available NAD+, the macronutrients cannot be converted into cellular energy in the form of adenosine triphosphate (ATP). Studies have shown that depleted NAD+ levels triggers programmed cell death.

"The NAD enhanced all of my activities... Everything I do, I do with a little more joy. Life has been more fun... Everything seems to be 40 years old again."
- Previous patient, Pat 

NAD+ Activates Sirtuin Enzymes

 

Silent information regulators, also known as sirtuins, require NAD+ in order to be activated. There are seven different sirtuin enzymes that mainly function to turn on or off gene expression. Many of these genes are linked to regulating inflammation, along with enhancing energy metabolism and cell vitality. Sirtuins are known to play a protective role in neurodegeneration, and other inflammatory-related diseases.

Regulate Inflammation

 

The CD38 enzyme is a major regulator of NAD+, and inflammatory signals increase its production. CD38 is theorized to significantly deplete cellular NAD+ levels due to chronic inflammation during aging.

study has observed NAD+ levels significantly increase by up 10-20 fold by simply knocking down the CD38 enzyme. One of the functions of CD38 is to produce second messengers, including cADPR, which is known to regulate calcium within the cell. In order to produce one molecule of cADPR, one hundred molecules of NAD+ are consumed  by CD38. Expression of CD38, along with unavailable NAD+, has a domino effect that inhibits sirtuin 1.

Replenishing your cells with NAD+ may help reduce inflammation and provide your body the enzymatic currency it needs.