Common Side Effects of IV NAD+ Therapy

IV NAD+ therapy (IV NAD+) can be a long process and produce physical sensations throughout the body. For some, the NAD+ creates a euphoric and giddy feeling coupled with spontaneous giggles. For others, it can be a little more difficult for the body to process. There is no way of knowing how your body will respond to the NAD+ until you try it for yourself. These are some of the common side effects of IV NAD+ Therapy.

side effects of IV NAD+ therapy

Muscle Cramps ( Side Effects of IV NAD+ Therapy)

A very common side effect of the IV NAD+ therapy is muscle cramping. Muscles in the stomach, back, shoulders, legs and arms can feel sore as if you just did some heavy lifting in the gym. Some doctors prescribe muscle relaxers to alleviate the muscle cramping, but mild stretching, heating pads and essential oils are another remedy to explore.

The Wave

Unlike the rush a surfer experiences the moment before catching the perfect wave, the NAD+ wave can be unpleasant for some. Imagine a mild wave of pressure rolling over your entire body. For someone who is new to receiving NAD+, the wave can be less than comfortable, but don’t let the wave deter you from receiving the treatment! The wave lasts for a few brief moments before it subsides.

side effects of IV NAD+ therapy

The Rush

Patients who decide to push their luck and try to cut down their infusion time by increasing the drip rate will experience a rush like never before. Rapid heart rate, headache, and a jolt of energy followed by a wave of pressure can be a very unpleasant feeling.

It is important to remember that the NAD+ needs to be administered at a slow rate for health benefits. The more obvious reason is to reduce any discomfort one may experience with a rush of NAD+, but more importantly, it is rumored that the NAD+ is more readily absorbed into the cells at a slower rate. In other words, a slow drip will have more therapeutic benefit.

Congested Sinus

While not everyone has an emotional experience or breakthrough when receiving the therapy, it is still a good idea to have a box of tissues on hand. Congested sinuses and a runny nose often result from the NAD+.


An increase in appetite can be a hit or miss for most individuals. Some people enjoy snacking throughout the treatment, whereas some people prefer to fast for the day. Either way, we recommend bringing some snacks just in case.


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